Mechanisms controlling the volume of pleural fluid and extravascular lung water

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Mechanisms controlling the volume of pleural fluid and extravascular lung water.

Pleural and interstitial lung fluid volumes are strictly controlled and maintained at the minimum thanks to the ability of lymphatics to match the increase in filtration rate. In the pleural cavity, fluid accumulation is easily accommodated by retraction of lung and chest wall (high compliance of the pleural space); the increase of lymph flow per unit increase in pleural fluid volume is high du...

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Extravascular Lung Water and Acute Lung Injury

Acute lung injury carries a high burden of morbidity and mortality and is characterised by nonhydrostatic pulmonary oedema. The aim of this paper is to highlight the role of accurate quantification of extravascular lung water in diagnosis, management, and prognosis in "acute lung injury" and "acute respiratory distress syndrome". Several studies have verified the accuracy of both the single and...

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On defining the pulmonary extravascular water volume.

To evaluate the effect of diffusion on the pulmonary extravascular water volume determined from indicator dilution studies, simultaneous comparisons of the pulmonary extravascular distribution volumes of tritiated water (THO) and of three lipid soluble substances with higher molecular weights were made. In 21 studies on pentobarbital-anesthetized dogs, the distribution volume of antipyrine (AP)...

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Extravascular lung water in the exercising horse.

Seven Standardbred horses were exercised on a treadmill at speeds (approximately 12 m/s) producing maximal heart rate, hypoxemia, and a mean pulmonary arterial pressure of approximately 75 mmHg. Extravascular lung water was measured by using transients in temperature and electrical impedance of the blood caused by a bolus injection of cold saline solution. Lung water was approximately 3 ml/kg b...

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Pathophysiology of Extravascular Water in the Pleural Cavity and in the Lung Interstitium After Lung Thoracic Surgery

Thoracic surgery implies a considerable imbalance of fluid dynamics in the pleural space and in the lung interstitium, and this is of relevance when considering that the volume of water in these compartments is physiologically very low thanks to very powerful mechanisms of control able to offset potential causes leading to an increase in this volume. There are reasons to believe that severe com...

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ژورنال

عنوان ژورنال: European Respiratory Review

سال: 2009

ISSN: 0905-9180,1600-0617

DOI: 10.1183/09059180.00002709